Triple Action NAD+ Support with Nicotinamide Riboside, Trans-Resveratrol, and Quercetin

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How We Compare

See how our formula stacks up against other NAD+ / NR supplements on the market.

Ingredient Benefits
Plantanium
Other Supplements
Multi-Targeted Formula
Backed by Science
Bio-Optimized Ingredients
Balanced Ingredient Dosage
3rd Party Lab Certification
Multiple Supporting Ingredients

Based on internal formulation review of leading NAD+ / Nicotinamide Riboside supplements. Individual results may vary.

Targets key root causes of low NAD+

Unlock the power of Platinum NAD+ Nicotinamide Riboside as it revitalizes your body's core, addressing the root causes of low energy to restore vitality and fuel your day like never before.

Certain genes regulate sirtuins

Which are crucial for aging-related processes like DNA repair, inflammation regulation, and metabolism. Genetic variations in SIRT1 or other sirtuins can impact how well the body maintains NAD+ levels and uses it for cellular repair, potentially affecting lifespan and age-related disease susceptibility.

Improved metabolism

Exercise, diet, and sleep influence sirtuin activity by modulating NAD+ levels. For instance, exercise increases the production of NAMPT, an enzyme involved in NAD+ biosynthesis, which in turn activates sirtuins like SIRT1. A nutrient-rich diet can also support NAD+ and enhance sirtuin function, promoting longevity, improved metabolism, and cellular repair.

Maintaining NAD+ levels

Exposure to environmental stressors like UV radiation and pollution can increase DNA damage, which activates sirtuins to repair cells. However, these stressors also consume NAD+, reducing its availability for sirtuin activity. Maintaining NAD+ levels through a healthy environment can help ensure that sirtuins remain active and effective in countering cellular damage.

Maintaining healthy NAD+

Chronic inflammation reduces NAD+ levels, which in turn impacts sirtuin activity. Sirtuins play a key role in modulating inflammation, and when NAD+ is depleted, their ability to control inflammatory responses is compromised. Maintaining healthy NAD+ levels supports sirtuin-mediated regulation of inflammation, potentially slowing the aging process.

NAD+ synthesis can impair

Hormones like insulin, estrogen, and testosterone influence sirtuin activity. For example, SIRT1 is known to be involved in regulating insulin sensitivity, while estrogen has been shown to enhance sirtuin activity, particularly in females. Hormonal imbalances that reduce NAD+ synthesis can impair sirtuin function, contributing to age-related conditions like metabolic disorders.

Social and Psychological Factors

Stress and social isolation can affect behaviors like sleep, exercise, and nutrition, which in turn influence sirtuin activity. High levels of stress can reduce NAD+ levels, impairing sirtuins like SIRT1 that regulate stress responses and protect against cellular damage. Positive social interactions and mental health support can help maintain sirtuin function by promoting healthier lifestyle choices.

Chronic Diseases and Medical Conditions

Chronic diseases like diabetes and neurodegenerative disorders reduce NAD+ levels, impairing sirtuin activity. For example, SIRT1 helps protect against neurodegeneration by promoting DNA repair and regulating inflammation. As NAD+ declines, sirtuin activity decreases, worsening the progression of these diseases and contributing to the aging process.

Lead to age-related gene expression

Epigenetic changes can influence sirtuin expression and function. Sirtuins themselves regulate epigenetic modifications by modifying histones, which affects gene expression related to aging, stress resistance, and metabolism. When NAD+ levels drop with age, sirtuins are less able to regulate these epigenetic changes, which can lead to age-related gene expression patterns.

Biological Theories of Aging

The wear-and-tear theory and programmed theories of aging both recognize the importance of sirtuins in mitigating the effects of aging. Sirtuins help repair cellular damage and regulate metabolic processes, but as NAD+ levels decline with age, their activity decreases, leading to the accumulation of cellular damage. This depletion of NAD+ and sirtuin activity is thought to contribute to the aging process and age-related diseases.

NAD+ levels supports

NAD+ is essential for DNA repair, particularly through enzymes like PARP that use NAD+ to fix DNA damage. As we age, DNA damage accumulates, and the body's repair capacity declines, leading to NAD+ depletion. This reduces the availability of NAD+ for other functions like sirtuin activation, further impairing cellular health. Efficient DNA repair is crucial for longevity, and maintaining NAD+ levels supports this process, helping to prevent mutations and cellular dysfunction that contribute to aging. Reduced NAD+ availability hampers repair, accelerating the aging process.

Introducing Our Solution


Efficacy backed by peer-reviewed published research

Our Platinum NAD+ Nicotinamide Riboside is manufactured in the USA in an FDA-registered, GMP-certified facility. Each batch is tested for heavy metals, microbial contaminants, and purity.

Supports Longevity and Cellular Renewal: NAD+ Triple Action NR helps with healthy aging, disease resistance, and cognitive longevity for maximum effectiveness by enhancing the repair processes within your cells, leaving you looking and feeling younger and fresher than ever before.

Best for an Active Lifestyle and Good Health: Whether you want better stamina, sharper thinking, or simply feeling GREAT! Triple Action NR is known to suit your health needs and lifestyle to ensure proper maintenance of peak performance and health for many years.

High Potency Formula for Maximum Effectiveness: Each serving brings a robust blend of 1000mg of Nicotinamide Riboside, 200mg of resveratrol, and 100mg of quercetin. Synergistic ingredients ensure unmatched support for cellular health in each dose—leading you to the best results with every dosage.


Backed by 25+ years of research & innovation

From the NAD+ authority trusted by physicians, athletes, researchers, and a Nobel Prize-winning biochemist.

45+ Human Clinical Studies
50+ Patents
500+ Published Scientific Studies
300+ Global Research Collaborations
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Helping Build Your

Nu You!

212 Reviews

Frequently Asked Questions

+ What are the primary benefits of this supplement?

This supplement is designed to:

  • Enhance cellular energy by increasing NAD+ levels (Nicotinamide Riboside).
  • Provide antioxidant and anti-inflammatory support (Resveratrol and Quercetin).
  • Promote cardiovascular health and improve circulation.
  • Support immune function and reduce oxidative stress.
  • Enhance brain health, cognitive function, and potentially delay age-related cognitive decline.
  • Contribute to anti-aging and longevity by supporting cellular repair mechanisms.
  • Increased cellular energy and metabolism.
  • Support for mitochondrial health.
  • Potential anti-aging effects through enhanced NAD+ levels.
  • Improved exercise recovery and endurance.
  • Reduced Inflammation
  • Enhanced Brain Health and Neuroprotection
  • Synergistic Antioxidant Protection
  • Immune System Support
  • Support for Senescent Cell Clearance
  • Metabolic and Weight Management
  • Improved Skin Health
  • Hormonal and Endocrine Balance
+ How long does it take to see results?
  • Short-term effects (2–4 weeks): Increased energy, improved recovery, and reduced fatigue.
  • Mid-term effects (1–3 months): Enhanced cognitive function, improved skin health, and reduced inflammation.
  • Long-term effects (3–6+ months): Anti-aging benefits, improved cardiovascular and metabolic health, and resilience against chronic conditions.
+ How should I take this supplement?
  • Dosage: Follow the recommended dosage. Ensure it aligns with your healthcare provider's advice.
  • Timing: Can be taken without food. However, taking with or after a meal to enhance absorption and minimize potential stomach upset if you are sensitive to the ingredients.
+ Can I take this supplement long-term?

Yes, this supplement is generally safe for long-term use when taken as directed. However, it is advisable to consult a healthcare professional periodically to evaluate its ongoing benefits and
safety.

+ Are there any side effects?

The dosage is designed to be generally safe with adverse side effects. Increased dosage may have potential side effects that may include:

  • Nicotinamide Riboside (NR): Digestive upset, mild headaches, or fatigue (especially at
    high doses than 1000mg).
  • Resveratrol: Gastrointestinal discomfort, mild headaches, or interactions with blood-
    thinning medications.
  • Quercetin: Nausea or stomach upset at higher doses.

If you experience persistent or severe side effects, discontinue use and consult a healthcare
professional.

+ Are there any side Are there any interactions with medications?effects?

Yes, the components may interact with:

  • Blood thinners (e.g., warfarin, aspirin): Resveratrol and quercetin may enhance their effects.
  • Blood pressure medications: They can have additive effects on lowering blood pressure.
  • Antibiotics or CYP3A4 metabolized drugs: Quercetin may interfere with their
    metabolism.

Always consult your healthcare provider if you are taking medications.

+ Can this supplement help with weight management?

Yes, the ingredients may support weight management by:

  • Improving mitochondrial function and energy metabolism (Nicotinamide Riboside).
  • Enhancing insulin sensitivity and reducing fat accumulation (Resveratrol and Quercetin).
+ Can I combine this supplement with other vitamins or supplements?

Yes, it can be combined with complementary supplements such as:

  • Vitamin D and omega-3s for immune and cardiovascular support.
  • CoQ10 or PQQ for additional mitochondrial support. However, avoid taking overlapping supplements with high doses of similar ingredients to prevent over-supplementation.
+ Is this supplement safe for older adults?

Yes, this supplement is often used by older adults to promote healthy aging, cognitive function, and cardiovascular health. It is particularly beneficial for those looking to maintain energy levels and mitigate age-related decline.

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Disclaimer: This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.